The presentation will address the primary open PIDs used in research, as well as demonstrating how they are being used in the Latin America region and how, in combination, they can increase trust in research and the research infrastructure. It will talk about the benefits of persistent identifiers used in Latin America and how their adoption contributes to open science and a more open and robust framework that strengthens the research ecosystem. Use cases and their benefits will be presented with the interoperability of the different open persistent identifiers.